Treatment Comparison
EBOO vs DFPP: Understanding the Difference
EBOO and double filtration plasmapheresis both involve an extracorporeal circuit, but they use different processes and should not be treated as interchangeable options. A physician assessment is necessary before either is considered.

How EBOO is approached
EBOO involves circulating blood through a sterile closed circuit where oxygenation and ozonation are managed by trained clinical staff. Monitoring and protocol decisions are individualised.
How DFPP is approached
DFPP separates plasma from cellular blood components, then passes the plasma through a second filter selected for the clinical purpose before the components are returned. This two-stage filtration process requires specialised equipment and supervision.
Important differences
The core difference is what happens within the circuit: EBOO centres on controlled oxygenation and ozonation, while DFPP centres on plasma separation and selective filtration. Equipment, preparation, visit length and monitoring needs may therefore differ.
- Neither option should be selected from a website description alone.
- One is not automatically more suitable or more effective than the other.
- Your medical history and assessment findings guide the discussion.
How a physician helps you decide
A consultation reviews your goals alongside current health, medicines, previous diagnoses and relevant test results. The physician may recommend one option, discuss an alternative, request further assessment or advise against treatment.
Evidence and expectations
The evidence base and accepted clinical uses differ across extracorporeal procedures. Ask which evidence applies to your circumstances, what alternatives exist and how progress would be evaluated. Individual responses vary and no outcome is guaranteed.
Related program
DFPP Plasmapheresis
Explore the program overview, then book a physician consultation to discuss individual suitability.
Medical Disclaimer
This article is for educational purposes and does not replace medical consultation, diagnosis or care. Individual suitability must be assessed by a physician. Treatment plans are personalised, individual responses vary and no outcome is guaranteed.
